Proteomic Classification of Breast Cancer
نویسندگان
چکیده
منابع مشابه
Title: Proteomic Classification of Breast Cancer
Being a significant health problem that affects patients in various age groups, breast cancer has been extensively studied to date. Recently, molecular breast cancer classification has advanced significantly with the availability of genomic profiling technologies. Proteomic technologies have also advanced from traditional protein assays including enzyme-linked immunosorbent assay, immunoblottin...
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Breast cancer is traditionally considered as a heterogeneous disease. Molecular profiling of breast cancer by gene expression studies has provided us an important tool to discriminate a number of subtypes. These breast cancer subtypes have been shown to be associated with clinical outcome and treatment response. In order to elucidate the functional consequences of altered gene expressions relat...
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With an advance in technologies, different tumor features have been collected for Breast Cancer (BC) diagnosis, processing of dealing with large data set suffers some challenges which include high storage capacity and time require for accessing and processing. The objective of this paper is to classify BC based on the extracted tumor features. To extract useful information and diagnose the tumo...
متن کاملProteomic approach to breast cancer.
BACKGROUND Breast cancer is the most common cancer affecting women worldwide. Despite tremendous advances in screening, diagnosis, and treatment, the causes of this disease remain elusive and complex. Proteomics is a rapidly developing field that can explore the heterogeneity of breast cancer and supplement the wealth of information gained from genomics. METHODS This article serves as an over...
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Cancer is intimately connected with the intrinsic processes of ageing at several important levels. Firstly, incidence rates for the great majority of cancers rise steeply with advancing age. Secondly, there is an important overlap between the roles of molecular damage accumulation in ageing and cancer. Thirdly, there is a powerful inter-species correlation between longevity, rate of DNA repair ...
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ژورنال
عنوان ژورنال: Current Drug Targets
سال: 2012
ISSN: 1389-4501
DOI: 10.2174/138945012803530080